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Products for use in the clinical diagnosis of viral infections, including SARS-CoV-2, the virus that causes COVID-19, by simultaneously measuring multiple analytes from a single sample.
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The Meso Scale Discovery V-PLEX Cytokine Panel 1 (Mouse) Kit is a multiplex immunoassay that simultaneously measures mouse IFN- IL-10 IL-12p70 IL-1 IL-2 IL-4 IL-5 IL-6 KC/GRO and TNF- in serum plasma and culture supernatants It utilizes electrochemiluminescent detection technology for high sensitivity and broad dynamic range The kit includes a 96-well plate coated with capture antibodies detection antibodies calibrators controls 10X diluent read buffer wash buffer and plate seals sufficient for one 96-well plate This assay allows for the accurate quantitation of multiple cytokines from a small sample volume
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The V-PLEX SARS-CoV-2 Key Variant Spike Panel 1 (ACE2) Kit from Meso Scale Diagnostics is a multiplex immunoassay panel that allows for the simultaneous detection and quantitation of antibodies to the receptor binding domain (RBD) of the SARS-CoV-2 spike protein and its key variants (Alpha Beta Gamma Delta Omicron BA 1 Omicron BA 2/BA 5) The kit contains a 96-well plate coated with recombinant RBD antigens detection antibodies assay diluent wash buffer read buffer and calibrators and controls The electrochemiluminescence immunoassay allows sensitive and accurate measurement of IgG antibodies that block the interaction between RBD and ACE2 receptor
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The V-PLEX Human Insulin Kit from Meso Scale Discovery is a multiplex immunoassay for measuring insulin in human serum plasma saliva and cell culture samples It includes a 96-well plate with capture antibodies detection antibodies with an electrochemiluminescent label calibrators and necessary reagents The detection range is 50-25 000 pg/mL with minimal proinsulin cross-reactivity The assay takes about 3 5 hours and requires an MSD instrument like QuickPlex SECTOR Imager or SQ 120 It offers a sensitive specific and high-throughput method for insulin measurement
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Meso Scale Discovery provides V-PLEX immunoassay kits for mouse samples including cytokine chemokine growth factor and biomarker panels These multiplex assays detect multiple analytes from a single sample using MSD s SECTOR technology offering high sensitivity and a broad dynamic range Compatible with serum plasma and cell culture supernatants V-PLEX kits range from 2-plex to 10-plex with over 50 mouse analytes available The assays are fast simple and can be read on MSD s QuickPlex SQ 120 instruments efficiently generating biomarker data from limited samples
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The Mesoscale K15669U-4 is a 4-channel 16-bit 250 kS/s simultaneous sampling data acquisition module It has 4 analog voltage input channels with programmable input ranges of 10 V 5 V 2 V and 1 V The module has 16-bit resolution and a maximum sampling rate of 250 kS/s It can perform 4-channel simultaneous sampling and streaming to PC memory through USB 2 0 The K15669U-4 has software-selectable AC/DC coupling and input impedances of 1 M and 50 It is compatible with both Windows and Linux operating systems The module is bus-powered and compact in size
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The Meso Scale Diagnostics V-PLEX SARS-CoV-2 Key Variant Spike Panel 1 MSIGM Kit is an immunoassay that detects antibodies to the spike protein of SARS-CoV-2 variants in human serum plasma and dried blood spot samples This 25-plate kit includes reagents to run the assay on the MSD platform allowing for quantitative measurement of IgG antibodies binding to the spike proteins of the original Wuhan strain as well as the Alpha Beta Gamma Delta and Omicron variants The kit enables investigation of the antibody response to emerging SARS-CoV-2 variants
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The Mesoscale K15630U-4 is a 4-channel 30 MHz bandwidth 14-bit resolution digitizer with a maximum sampling rate of 250 MS/s It has a 1 GB on-board acquisition memory and features programmable input ranges DC offset adjustment and software-selectable AC/DC input coupling This PCIe digitizer card has a low noise floor and is well-suited for high-speed waveform capture and data acquisition applications The K15630U-4 utilizes a Xilinx Virtex-5 FPGA and Mesoscale s StreamStor technology for continuous streaming to host memory at rates up to 1 6 GB/s
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The Meso Scale Discovery V-PLEX Plus Viral Panel 1 Human Kit is a multiplex immunoassay that simultaneously detects antibodies to SARS-CoV-2 Influenza A Influenza B and RSV in human serum and plasma This assay uses electrochemiluminescence detection technology and provides quantitative results for each analyte in under 3 hours The kit includes a 96-well plate coated with antigens detection antibodies calibrators controls wash buffer read buffer and plate seals This assay can aid in the diagnosis of viral respiratory infections
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The V-PLEX Human TNF-beta Kit from Meso Scale Discovery is a multiplex immunoassay for measuring human TNF-beta in various biological fluids It uses electrochemiluminescence detection with high sensitivity up to 5 pg/mL in an antibody sandwich format The kit includes a 96-well plate with capture antibodies detection antibodies labeled with an electrochemiluminescent compound and calibrator solutions The assay takes about 3 hours and requires a Meso Scale Discovery instrument allowing rapid accurate quantification with minimal sample volume and hands-on time
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Meso Scale Discovery offers a wide variety of V-PLEX assay kits for measuring biomarkers in mouse samples The electrochemiluminescent immunoassays provide high sensitivity broad dynamic range and low sample volume requirements Kits are available for measuring cytokines chemokines growth factors soluble receptors and other analytes in mouse serum plasma cell culture supernatants and other sample types The V-PLEX platform enables multiplex analysis of up to 10 biomarkers per well from a single small-volume sample
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The V-PLEX Metabolic Panel 1 Human Kit from Meso Scale Diagnostics is a multiplex immunoassay kit that allows simultaneous quantitative measurement of 10 metabolic biomarkers from a single sample The kit includes a 96-well plate coated with capture antibodies detection antibodies calibrators controls diluent wash buffer read buffer and plate seals The 10 biomarkers measured are albumin total protein creatinine glucose AST ALT ALP total bilirubin BUN and CRP The electrochemiluminescent detection method provides high sensitivity and a broad dynamic range This kit allows efficient metabolic testing from small sample volumes
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The Meso Scale Discovery SARS-CoV-2 Spike BA 5 Protein is a recombinant protein corresponding to the spike protein of the SARS-CoV-2 Omicron BA 5 variant It can be used in immunoassays and as an immunogen for antibody generation The protein is produced in HEK293 cells and contains a His-tag for purification It is supplied lyophilized from a Tris buffer The molecular weight is approximately 150 kDa for the trimeric protein This reagent allows researchers to study immune responses to the BA 5 variant of SARS-CoV-2
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The Meso Scale Discovery V-PLEX Human IL-6 Kit is a multiplex immunoassay that measures levels of human interleukin 6 (IL-6) in serum plasma and cell culture supernatants This 4-plex assay uses electrochemiluminescence detection technology and provides high sensitivity broad dynamic range and requires low sample volume The kit includes a 96-well plate coated with capture antibodies detection antibodies labeled with MSD SULFO-TAG calibrators and controls Recommended sample diluent and wash buffer are sold separately This assay has high specificity and less than 0 3% cross-reactivity with other cytokines
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The Meso Scale Discovery V-PLEX Plus Human Insulin Kit is an electrochemiluminescent immunoassay for measuring human insulin in serum plasma and cell culture supernatants It includes a 96-well plate with capture antibodies detection antibodies with an electrochemiluminescent label calibrators diluent wash buffer read buffer and plate seals The assay range is 3 13-1000 pg/mL and takes about 3 5 hours It uses MSD s SULFO-TAG labels and MESO QuickPlex SQ 120 for detection The kit provides reagents for one 96-well plate allowing 40 samples in duplicate
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The Meso Scale Discovery V-PLEX SARS-CoV-2 Panel 2 (IgM) is an electrochemiluminescent immunoassay kit that detects IgM antibodies to SARS-CoV-2 in human serum and plasma It includes a 96-well plate coated with SARS-CoV-2 antigens detection antibodies calibrators controls diluent wash buffer read buffer and plate seals The assay has a testing time of approximately 3 hours and 30 minutes and a sample volume requirement of 50 L It has a reportable range of 50-100 000 U/mL The kit includes sufficient reagents for one 96-well plate
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